Hs6st2 - heparan sulfate 6-O-sulfotransferase 2

Enables heparan sulfate 6-O-sulfotransferase activity. Acts upstream of or within heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; embryo mesenchyme; eye; foot bone; and urethra. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome. Orthologous to human HS6ST2 (heparan sulfate 6-O-sulfotransferase 2). [provided by Alliance of Genome Resources, Apr 2022]