Hs6st1 - heparan sulfate 6-O-sulfotransferase 1

Enables heparan sulfate 6-O-sulfotransferase activity. Acts upstream of or within blood vessel development; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; and lung alveolus development. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]