Mapk3 - mitogen activated protein kinase 3

Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonic acid metabolic process; decidualization; and peptidyl-serine phosphorylation. Located in caveola; cytosol; and nucleoplasm. Part of protein-containing complex. Used to study gastric ulcer; middle cerebral artery infarction; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]