Rab27a - RAB27A, member RAS oncogene family

Enables protein domain specific binding activity. Predicted to be involved in several processes, including complement-dependent cytotoxicity; regulation of vesicle-mediated transport; and secretion by cell. Predicted to act upstream of or within several processes, including leukocyte degranulation; melanocyte differentiation; and pigment granule localization. Located in Weibel-Palade body; apical plasma membrane; and secretory granule membrane. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Orthologous to human RAB27A (RAB27A, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]