Gria1 - glutamate ionotropic receptor AMPA type subunit 1

Enables several functions, including AMPA glutamate receptor activity; enzyme binding activity; and signaling receptor binding activity. Involved in several processes, including cellular response to organonitrogen compound; long-term memory; and modulation of chemical synaptic transmission. Located in several cellular components, including dendrite; endosome membrane; and postsynaptic density. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane and integral component of presynaptic membrane. Used to study hyperhomocysteinemia. Biomarker of epilepsy; hepatic encephalopathy; status epilepticus; and visual epilepsy. Orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1). [provided by Alliance of Genome Resources, Apr 2022]