Grem1 - gremlin 1, DAN family BMP antagonist

Predicted to enable several functions, including BMP binding activity; protein homodimerization activity; and signaling receptor activator activity. Involved in several processes, including negative regulation of cell growth; negative regulation of monocyte chemotaxis; and positive regulation of angiogenesis. Acts upstream of or within negative regulation of osteoblast differentiation. Located in cell surface and extracellular space. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]