Angptl3 - angiopoietin-like 3

Predicted to enable growth factor activity; integrin binding activity; and phospholipase inhibitor activity. Involved in response to hormone. Predicted to be located in Golgi apparatus; cell surface; and early endosome. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to human ANGPTL3 (angiopoietin like 3). [provided by Alliance of Genome Resources, Apr 2022]