Amer1 - APC membrane recruitment protein 1

Predicted to enable beta-catenin binding activity; beta-catenin destruction complex binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of cellular protein metabolic process and regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within adipose tissue development; bone development; and mesenchymal cell differentiation involved in kidney development. Predicted to be located in nuclear body. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in osteopathia striata with cranial sclerosis. Orthologous to human AMER1 (APC membrane recruitment protein 1). [provided by Alliance of Genome Resources, Apr 2022]