Fancb - FA complementation group B

Predicted to be involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via homologous recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to act upstream of or within cellular response to camptothecin and cellular response to xenobiotic stimulus. Predicted to be part of Fanconi anaemia nuclear complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). [provided by Alliance of Genome Resources, Apr 2022]