H2ax - H2A.X variant histone

Predicted to enable damaged DNA binding activity; enzyme binding activity; and histone binding activity. Involved in several processes, including cellular response to gamma radiation; cellular senescence; and cerebral cortex development. Located in nucleus. Used to study hypertension; status epilepticus; and transient cerebral ischemia. Biomarker of liver benign neoplasm. Orthologous to human H2AX (H2A.X variant histone). [provided by Alliance of Genome Resources, Apr 2022]