Ncf4 - neutrophil cytosolic factor 4

Predicted to enable phosphatidylinositol-3-phosphate binding activity and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in superoxide anion generation. Predicted to be located in cytosol and endosome membrane. Predicted to be part of NADPH oxidase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive chronic granulomatous disease cytochrome b-positive type III and rheumatoid arthritis. Orthologous to human NCF4 (neutrophil cytosolic factor 4). [provided by Alliance of Genome Resources, Apr 2022]