Gdf3 - growth differentiation factor 3

Predicted to enable cytokine activity and protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of fat cell differentiation; regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including anterior/posterior axis specification; negative regulation of myoblast differentiation; and notochord development. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome 3 and isolated microphthalmia 7. Orthologous to human GDF3 (growth differentiation factor 3). [provided by Alliance of Genome Resources, Apr 2022]