Nod1 - nucleotide-binding oligomerization domain containing 1

Predicted to enable CARD domain binding activity; pattern recognition receptor activity; and protein homodimerization activity. Involved in positive regulation of cell death; positive regulation of cytokine production; and positive regulation of nitric-oxide synthase activity. Predicted to be located in basolateral plasma membrane; cytosol; and phagocytic vesicle. Predicted to be anchored component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]