Tlx1 - T-cell leukemia, homeobox 1

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; positive regulation of transcription by RNA polymerase II; and spleen development. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adult T-cell leukemia. Orthologous to human TLX1 (T cell leukemia homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]