Scube2 - signal peptide, CUB domain and EGF like domain containing 2

Predicted to enable hedgehog family protein binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including positive regulation of chondrocyte proliferation; positive regulation of osteoblast differentiation; and positive regulation of smoothened signaling pathway. Predicted to be active in cell surface and extracellular space. Orthologous to human SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]