Themis - thymocyte selection associated

Predicted to be involved in T cell receptor signaling pathway; negative T cell selection; and positive T cell selection. Predicted to be located in cell-cell junction. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm and nucleus. Used to study inflammatory bowel disease. Orthologous to human THEMIS (thymocyte selection associated). [provided by Alliance of Genome Resources, Apr 2022]