Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic cranial skeleton morphogenesis; gonad development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron differentiation; regulation of gene expression; and regulation of heart rate. Predicted to be active in nucleus. Orthologous to human IRX5 (iroquois homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]