Sting1 - stimulator of interferon response cGAMP interactor 1

Enables 2',3'-cyclic GMP-AMP binding activity. Involved in cellular response to organic cyclic compound and positive regulation of type I interferon production. Predicted to be located in several cellular components, including mitochondrial outer membrane; perinuclear region of cytoplasm; and peroxisome. Predicted to be integral component of endoplasmic reticulum membrane and integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane. Predicted to be active in autophagosome and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1). [provided by Alliance of Genome Resources, Apr 2022]