Predicted to enable cytokine activity and nodal binding activity. Predicted to be involved in several processes, including negative regulation of nodal receptor complex assembly; regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including anterior/posterior axis specification; cell migration involved in gastrulation; and response to retinoic acid. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including LEFTY1 (left-right determination factor 1). [provided by Alliance of Genome Resources, Apr 2022]