Mtrfr - mitochondrial translation release factor in rescue

Predicted to enable ribosomal large subunit binding activity and tRNA binding activity. Predicted to be involved in rescue of stalled ribosome. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 7 and hereditary spastic paraplegia 55. Orthologous to human MTRFR (mitochondrial translation release factor in rescue). [provided by Alliance of Genome Resources, Apr 2022]