Pirt - phosphoinositide-interacting regulator of transient receptor potential channels

Predicted to enable phosphatidylinositol bisphosphate binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and transmembrane transporter binding activity. Predicted to be involved in phosphatidylinositol-mediated signaling and positive regulation of cation channel activity. Predicted to act upstream of or within behavioral response to pain and response to heat. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human PIRT (phosphoinositide interacting regulator of transient receptor potential channels). [provided by Alliance of Genome Resources, Apr 2022]