Apcdd1 - adenomatosis polyposis coli down-regulated 1

Predicted to enable Wnt-protein binding activity and identical protein binding activity. Involved in regulation of odontogenesis of dentin-containing tooth. Acts upstream of or within astrocyte cell migration. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; branchial arch; ear; and reproductive system. Human ortholog(s) of this gene implicated in hypotrichosis 1. Orthologous to human APCDD1 (APC down-regulated 1). [provided by Alliance of Genome Resources, Apr 2022]