Dnmt3b - DNA methyltransferase 3 beta

Enables DNA binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to hyperoxia; and response to alkaloid. Located in cytoplasm and nucleus. Biomarker of anxiety disorder; congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune disease (multiple); carcinoma (multiple); immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta). [provided by Alliance of Genome Resources, Apr 2022]