Gja6 - gap junction protein, alpha 6

Predicted to enable several functions, including alpha-tubulin binding activity; beta-catenin binding activity; and gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to be located in several cellular components, including gap junction; intercalated disc; and tight junction. Predicted to be part of connexin complex. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive craniometaphyseal dysplasia; congenital heart disease (multiple); erythrokeratodermia variabilis (multiple); oculodentodigital dysplasia; and palmoplantar keratoderma and congenital alopecia 1. Orthologous to several human genes including GJA1 (gap junction protein alpha 1). [provided by Alliance of Genome Resources, Apr 2022]