Spink2 - serine peptidase inhibitor, Kazal type 2

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in acrosome assembly and negative regulation of serine-type endopeptidase activity. Predicted to act upstream of or within several processes, including fertilization; gamete generation; and seminiferous tubule development. Predicted to be located in acrosomal vesicle and neuron projection. Human ortholog(s) of this gene implicated in spermatogenic failure 29. Orthologous to human SPINK2 (serine peptidase inhibitor Kazal type 2). [provided by Alliance of Genome Resources, Apr 2022]