C4b - complement C4B (Chido blood group)

Predicted to enable carbohydrate binding activity and complement component C1q complex binding activity. Predicted to be involved in complement activation; detection of molecule of bacterial origin; and positive regulation of apoptotic cell clearance. Predicted to act upstream of or within immunoglobulin mediated immune response. Located in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement component 4b deficiency; and renal cell carcinoma. Orthologous to human C4B (complement C4B (Chido blood group)). [provided by Alliance of Genome Resources, Apr 2022]