Flrt2 - fibronectin leucine rich transmembrane protein 2

Enables chemorepellent activity and fibroblast growth factor receptor binding activity. Involved in basement membrane organization; cell adhesion involved in heart morphogenesis; and fibroblast growth factor receptor signaling pathway. Acts upstream of or within axon guidance; positive regulation of synapse assembly; and regulation of neuron migration. Located in cell-cell junction and extracellular space. Is integral component of plasma membrane. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system epithelium; branchial arch; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human FLRT2 (fibronectin leucine rich transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]