Enables orexin receptor activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study narcolepsy. Orthologous to human HCRTR2 (hypocretin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]