Frmd7 - FERM domain containing 7

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in regulation of neuron projection development. Acts upstream of or within several processes, including negative regulation of stress fiber assembly; positive regulation of lamellipodium assembly; and positive regulation of small GTPase mediated signal transduction. Located in growth cone and neuronal cell body. Is expressed in brain; eye; heart; and lung. Used to study congenital nystagmus 1. Human ortholog(s) of this gene implicated in congenital nystagmus 1. Orthologous to human FRMD7 (FERM domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]