Prdm14 - PR domain containing 14

Enables RNA binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in germ cell development; positive regulation of flagellated sperm motility; and positive regulation of stem cell population maintenance. Acts upstream of or within several processes, including histone H3-R26 methylation; inner cell mass cell fate commitment; and regulation of nucleobase-containing compound metabolic process. Located in nucleus. Is expressed in several structures, including hemolymphoid system; intestine; liver; lung; and yolk sac. Orthologous to human PRDM14 (PR/SET domain 14). [provided by Alliance of Genome Resources, Apr 2022]