Acts upstream of or within determination of left/right symmetry and heart development. Is active in cytosol. Is expressed in brain; nasal cavity respiratory epithelium; and respiratory system epithelium. Used to study Kartagener syndrome; primary ciliary dyskinesia 21; and visceral heterotaxy. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21. Orthologous to human DRC1 (dynein regulatory complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]