Lrch1 - leucine-rich repeats and calponin homology (CH) domain containing 1

Involved in cellular response to chemokine; negative regulation of GTPase activity; and negative regulation of T cell migration. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and hemolymphoid system gland. Used to study multiple sclerosis. Orthologous to human LRCH1 (leucine rich repeats and calponin homology domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]