Ift81 - intraflagellar transport 81

Predicted to enable tubulin binding activity. Predicted to be involved in intraciliary transport involved in cilium assembly; regulation of smoothened signaling pathway; and spermatogenesis. Predicted to be located in ciliary basal body; sperm midpiece; and sperm principal piece. Predicted to be part of intraciliary transport particle B. Predicted to be active in centrosome and cilium. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Orthologous to human IFT81 (intraflagellar transport 81). [provided by Alliance of Genome Resources, Apr 2022]