Hyal1 - hyaluronidase 1

Predicted to enable hyaluronan synthase activity and hyalurononglucosaminidase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; hyaluronan metabolic process; and regulation of cell growth. Predicted to act upstream of or within embryonic skeletal joint morphogenesis. Predicted to be located in extracellular space; hyaluranon cable; and lysosome. Predicted to be active in cytoplasmic vesicle. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in mucopolysaccharidosis and mucopolysaccharidosis IX. Orthologous to human HYAL1 (hyaluronidase 1). [provided by Alliance of Genome Resources, Apr 2022]