Mafa - MAF bZIP transcription factor A

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including insulin secretion; nitric oxide mediated signal transduction; and response to glucose. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Biomarker of diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A). [provided by Alliance of Genome Resources, Apr 2022]