Fbxo7 - F-box protein 7

Predicted to enable several functions, including enzyme binding activity; protein heterodimerization activity; and ubiquitin ligase-substrate adaptor activity. Involved in negative regulation of neuron death and positive regulation of autophagy of mitochondrion. Predicted to be located in several cellular components, including Lewy body core; Lewy body corona; and Lewy neurite. Predicted to be part of SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7). [provided by Alliance of Genome Resources, Apr 2022]