Sptlc2 - serine palmitoyltransferase, long chain base subunit 2

Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in adipose tissue development; ceramide biosynthetic process; and sphingosine biosynthetic process. Predicted to act upstream of or within positive regulation of lipophagy; sphinganine biosynthetic process; and sphingomyelin biosynthetic process. Predicted to be integral component of membrane. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Orthologous to human SPTLC2 (serine palmitoyltransferase long chain base subunit 2). [provided by Alliance of Genome Resources, Apr 2022]