Flrt3 - fibronectin leucine rich transmembrane protein 3

Predicted to enable chemorepellent activity; fibroblast growth factor receptor binding activity; and protein homodimerization activity. Involved in neuron projection extension; response to axon injury; and synapse organization. Acts upstream of or within axon guidance. Located in axon terminus; postsynaptic density; and synaptic membrane. Is integral component of postsynaptic membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]