Aph1a - aph-1 homolog A, gamma secretase subunit

Predicted to enable endopeptidase activator activity; enzyme binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in several processes, including Notch receptor processing; amyloid-beta formation; and proteolysis. Predicted to act upstream of or within metanephros development. Located in cytoplasmic vesicle; mitochondrion; and synaptic membrane. Is integral component of presynaptic membrane. Orthologous to human APH1A (aph-1 homolog A, gamma-secretase subunit). [provided by Alliance of Genome Resources, Apr 2022]