Pip5k1a - phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Predicted to be involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Predicted to act upstream of or within fibroblast migration and phosphatidylinositol biosynthetic process. Predicted to be located in several cellular components, including lamellipodium; nuclear speck; and ruffle membrane. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]