Il21 - interleukin 21

Predicted to enable interleukin-2 receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; positive regulation of immune effector process; and tyrosine phosphorylation of STAT protein. Predicted to act upstream of or within positive regulation of cytokine production; positive regulation of lymphocyte activation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Biomarker of periodontal disease. Human ortholog(s) of this gene implicated in asthma; common variable immunodeficiency; hepatocellular carcinoma; and systemic lupus erythematosus. Orthologous to human IL21 (interleukin 21). [provided by Alliance of Genome Resources, Apr 2022]