Tbl1xr1 - TBL1X/Y related 1

Predicted to enable several functions, including beta-catenin binding activity; protein N-terminus binding activity; and transcription corepressor activity. Predicted to be involved in histone deacetylation; positive regulation of canonical Wnt signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including blastocyst hatching; fat pad development; and white fat cell differentiation. Predicted to be located in mitotic spindle and nucleus. Predicted to be part of histone deacetylase complex and transcription repressor complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 41. Orthologous to human TBL1XR1 (TBL1X receptor 1). [provided by Alliance of Genome Resources, Apr 2022]