Lcor - ligand dependent nuclear receptor corepressor

Predicted to enable several functions, including enzyme binding activity; estrogen receptor binding activity; and transcription corepressor binding activity. Predicted to be involved in cellular response to estradiol stimulus and positive regulation of histone H3-K27 trimethylation. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Orthologous to human LCOR (ligand dependent nuclear receptor corepressor). [provided by Alliance of Genome Resources, Apr 2022]