Ern2 - endoplasmic reticulum to nucleus signaling 2

Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; apoptotic chromosome condensation; and positive regulation of JUN kinase activity. Predicted to act upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum quality control compartment. Predicted to be part of IRE1-TRAF2-ASK1 complex. Orthologous to human ERN2 (endoplasmic reticulum to nucleus signaling 2). [provided by Alliance of Genome Resources, Apr 2022]