Fcar - Fc alpha receptor

Predicted to enable IgA binding activity and IgA receptor activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and positive regulation of cell death. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; granulomatosis with polyangiitis; and renal fibrosis. Orthologous to human FCAR (Fc fragment of IgA receptor). [provided by Alliance of Genome Resources, Apr 2022]