Involved in brain development. Located in dendritic spine membrane; perikaryon; and postsynaptic density. Biomarker of mesangial proliferative glomerulonephritis. Human ortholog(s) of this gene implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (integrin subunit alpha 8). [provided by Alliance of Genome Resources, Apr 2022]