Akr1c12 - aldo-keto reductase family 1, member C12
Alias:
BER1
TBER1
Akr1c13
LOCT364773
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
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Predicted to enable alditol:NADP+ 1-oxidoreductase activity; ketosteroid monooxygenase activity; and steroid dehydrogenase activity. Predicted to be involved in steroid metabolic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Apr 2022]