Fzd8 - frizzled class receptor 8

Predicted to enable several functions, including PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Predicted to act upstream of or within several processes, including T cell differentiation in thymus; angiogenesis; and positive regulation of JUN kinase activity. Predicted to be located in Golgi apparatus. Predicted to be part of Wnt-Frizzled-LRP5/6 complex. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Orthologous to human FZD8 (frizzled class receptor 8). [provided by Alliance of Genome Resources, Apr 2022]