Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant sensory ataxia 1. Orthologous to human RNF170 (ring finger protein 170). [provided by Alliance of Genome Resources, Apr 2022]