Tnfrsf10b - TNF receptor superfamily member 10b

Predicted to enable identical protein binding activity and protease binding activity. Involved in extrinsic apoptotic signaling pathway via death domain receptors; male gonad development; and response to organic cyclic compound. Located in membrane. Biomarker of colon cancer and osteoarthritis. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic cancer (multiple); and urinary bladder cancer. Orthologous to human TNFRSF10A (TNF receptor superfamily member 10a). [provided by Alliance of Genome Resources, Apr 2022]